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E-400 Select was formulated to capture the synergistic effects of combining natural-source vitamin E (d-alpha tocopherol) with selenium. Vitamin E has many beneficial effects as an antioxidant and offers protection for fatty acids and cholesterol circulating in the bloodstream.* Selenium is a trace mineral that functions in the body as a component of the antioxidant enzyme glutathione peroxidase. Vitamin E with selenium has been studied for its benefits in cardiovascular health, neurological health and prostate health.